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Last updated : 24/04/2026 - 17h35
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Inventiva: €230M in Cash but Less Than a Year of Financial Autonomy

The French biotech company reports its 2025 results with a record cash position thanks to two major fundraising events. However, accelerated cash burn and lack of commercial revenues reduce the company's financial autonomy to less than a year, ahead of the expected results of its flagship treatment for MASH in the fourth quarter of 2026.


Inventiva: €230M in Cash but Less Than a Year of Financial Autonomy

Financial Position and Fundraising Achievements

Inventiva closed the fiscal year 2025 with €99.3 million in cash and €131.6 million in short-term deposits, bringing its liquid resources to €230.9 million. This accumulation resulted from two major financing operations: the release of €115.6 million gross (€108.0 million net) in May 2025 as part of a structured financing announced in October 2024, and a capital raise of $172.5 million (€139.4 million net) conducted on the New York Stock Exchange in November 2025. In total, cash flows from financing reached €241.3 million in 2025, compared to €145.6 million in 2024. This increase reflects Inventiva’s determination to secure its resources ahead of the key publication of its NATiV3 pivotal clinical trial results.

Operational Cash Burn and Revenue Challenges

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Despite strengthening its cash portfolio, Inventiva sees its operational cash gap widening. The net cash consumption related to operational activities reached €104.9 million in 2025, up from €85.9 million in 2024, an increase of 22%. This acceleration is due to three factors: the net impact of the strategic reorganization plan implemented in 2025, the drop in revenues from the licensing agreement with CTTQ, and the increase in administrative expenses to €47.9 million (from €15.8 million in 2024), including €20.3 million in stock-based compensation. Concurrently, revenue plummeted to €4.5 million in 2025 from €9.2 million in 2024, while investments in marketing and commercial development jumped to €5.0 million (from €2.0 million in 2024), in preparation for a potential commercial launch.

Future Prospects and Strategic Adjustments

At the current rate of expenditure, Inventiva estimates that its cash and liquidity will fund its operations until the middle of the first quarter of 2027. This timeline perhaps explains why the group has adjusted its schedule for publishing the results of NATiV3 to the fourth quarter of 2026, in order to maximize its chances of quickly obtaining regulatory approval or securing strategic partnerships. CEO Andrew Obenshain assures that the regulatory and commercial infrastructure is 'progressing in parallel' to act 'swiftly' once the data is available. If the warrants for tranche 3 of the structured financing are fully exercised, Inventiva could generate an additional €116.0 million, extending its autonomy until the middle of the third quarter of 2027. However, there is no guarantee that these warrants will be exercised. For investors, the suspense remains: Inventiva must turn the NATiV3 trial into a commercial success before the countdown becomes critical.



Sector Santé · Biotechnologies · Pharmacie Biotechnologie


Assurance vie

Context

Period
  • Period: 9M 2025
Guidance from the release
  • Position de trésorerie au 30/09/2025 de 97,6 millions d’euros (plus 24,7 millions d’euros en dépôts à court terme) ; revenus de 4,5 millions d'euros sur les neuf premiers mois de 2025 principalement liés à CTTQ ; flux opérationnels consommés de - 76,3 millions d’euros et flux d'investissement de - 25 millions d’euros ; flux de financement positifs de 103,4 millions d’euros incluant le produit net de la deuxième tranche du financement structuré. Offre publique en novembre 2025 d’ADS apportant un produit net d’environ 139,3 millions d’euros et estimation d’un horizon de trésorerie jusqu’à fin T1 2027 (pouvant aller jusqu’à mi-T3 2027 si exercice intégral de la Tranche 3 pouvant apporter 116,0 millions d'euros).
Risks mentioned
  • Besoin de capitaux supplémentaires pour financer les opérations
  • Risque que la Société utilise ses ressources plus rapidement que prévu
  • Incertitudes et risques liés aux essais cliniques et aux autorisations réglementaires
  • Dépendance au succès du lanifibranor et des résultats de l'essai NATiV3
Opportunities identified
  • Produit net de l’offre publique en novembre 2025 d’environ 139,3 millions d’euros renforçant la trésorerie
  • Exercice potentiel de la Tranche 3 pouvant apporter jusqu’à 116,0 millions d'euros supplémentaires
  • Paiement d'étape et avoirs liés à l’accord avec CTTQ (10 M$ et 5 M$)
  • Résultats principaux de l’essai NATiV3 attendus au second semestre 2026

The information presented in this article is provided for informational purposes only and does not constitute an investment recommendation, an incentive to buy or sell a financial asset, or investment advice. Readers are invited to conduct their own research before making any decision.

Investments in the stock market involve risks, including the risk of capital loss. Past performance of an asset or market is no guarantee of future results. Any investment decision should be made taking into account your personal financial situation, objectives and risk tolerance.

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