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Last updated : 24/04/2026 - 17h35 (last close)
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Valneva Shares Fall 5.44% Midday After Previous Day's Surge

The stock of the Franco-Austrian biotech specializing in vaccines shows a significant decline this Friday, November 28, at midday.


Valneva Shares Fall 5.44% Midday After Previous Day's Surge

Valneva's stock falls 5.44% at midday this Friday, November 28, trading at 4.066 euros after having closed at 4.30 euros the previous day. Trading volumes remain moderate with 0.84% of the capital exchanged. This decline occurs in a positive stock market context, with the CAC 40 up by 0.2% at 8,115.29 points. Over the week, the stock still shows a gain of 7.85%, while the three-month performance is 7.74%. Over one year, the biotech has seen a spectacular rise of 120.3%, significantly outperforming the Paris index, which has only increased by 13.61% over the same period. Today's movement appears to be a natural profit-taking following the sharp increases recorded on Wednesday.

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This correction follows two major announcements made on Wednesday, November 26. Valneva first revealed positive final results for immunogenicity and safety from the Phase II study of VLA15, its vaccine candidate against Lyme disease developed in partnership with Pfizer. These data confirmed a strong immune response, with Stifel estimating an 80% probability of success for Phase III before potential commercialization. This announcement, well received by analysts, had propelled the stock up by 5.6% on Wednesday. Subsequently, the company announced the closure of its historic site in Nantes-Saint-Herblain to consolidate all its French activities in Lyon, where the headquarters will be transferred, while R&D will be centralized in Vienna, Austria. The Nantes site, which had about sixty employees, housed operational and preclinical R&D activities. This restructuring aims to enhance the operational efficiency of the group in a sector where cost control is crucial.

From a technical perspective, the stock is in a contrasting configuration. The RSI stands at 79, a high level indicating an overbought situation and suggesting a pause or consolidation in the short term. The MACD indicator, meanwhile, shows signs of recovery, with a positive histogram at 0.06, and the MACD line moving towards its signal line, although both remain in negative territory. The price trades slightly below its 50-day moving average positioned at 4.21 euros, but remains well above the 200-day moving average set at 3.44 euros, confirming an underlying bullish trend. Support and resistance levels are identified at 3.66 euros and 4.35 euros, respectively. It is worth noting that the stock remains under watch with a net short position representing 0.60% of the capital, and recent insider movements showing more disposals than purchases.



Sector Santé · Pharmacie Industrie Pharmaceutique


Assurance vie

Context

Period
  • Period: 9M 2025
Guidance from the release
  • Au troisième trimestre, nous avons continué à nous concentrer sur le renforcement de notre trésorerie, ce qui nous a permis de refinancer notre dette à des conditions financières plus avantageuses.
  • Chiffre d’affaires de 127,0 millions d’euros sur neuf mois (+8,9 %), ventes de 119,4 millions d’euros, trésorerie de 143,5 millions d’euros au 30/09/2025, perte nette 65,2 millions d’euros, EBITDA ajusté (37,7) millions d’euros. Guidance 2025 confirmée : chiffre d’affaires attendu entre 165 et 180 millions d’euros; ventes attendues entre 155 et 170 millions d'euros. Renforcement de la position financière via refinancement et ATMs; Phase 3 VALOR pour le vaccin Lyme en cours selon calendrier.
Risks mentioned
  • Suspension de la licence IXCHIQ ® aux États-Unis par la FDA (impact sur ventes segment voyageurs)
  • Risque de résultats cliniques défavorables pour les candidats (phase 3 VALOR pour Lyme, essais S4V2, VLA1601 incertitudes réglementaires)
  • Exposition aux fluctuations de change (impact négatif mentionné de 1,3 millions d’euros sur ventes, effets de change volontaires)
  • Dépendance à des partenaires de distribution et diminution des produits de tiers (arrêt de distribution de Rabipur/RabAvert et Encepur)
Opportunities identified
  • Résultats positifs potentiels de la Phase 3 VALOR (VLA15) pouvant mener à des demandes d'autorisation en 2026
  • Accord commercial avec CSL Seqirus en Allemagne pour stimuler la commercialisation des vaccins
  • Croissance des ventes d'IXCHIQ ® sur les marchés hors États-Unis et dans les PRFI (livraisons de substance active)
  • Potentiel du candidat S4V2 contre la shigellose (marché estimé > 500 millions de dollars/an)
  • Données positives de Phase 1 pour VLA1601 (Zika) et forte persistance d'anticorps pour IXCHIQ ® (95 % à 4 ans) comme avantage concurrentiel

The information presented in this article is provided for informational purposes only and does not constitute an investment recommendation, an incentive to buy or sell a financial asset, or investment advice. Readers are invited to conduct their own research before making any decision.

Investments in the stock market involve risks, including the risk of capital loss. Past performance of an asset or market is no guarantee of future results. Any investment decision should be made taking into account your personal financial situation, objectives and risk tolerance.

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