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Last updated : 06/11/2026 - 10h14
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Ipsen: Iqirvo normalizes ALP in 85.3% of Phase III patients, versus 23.3% on placebo

In a press release published on November 5, 2026, Ipsen unveiled the results of the Phase III ELSPIRE study, conducted in primary biliary cholangitis (PBC). The company presents the data as ones that “raise the bar” in this disease, and states that its treatment was “generally well tolerated”.


Ipsen: Iqirvo normalizes ALP in 85.3% of Phase III patients, versus 23.3% on placebo

Patients selected by ALP level, compared with placebo

The ELSPIRE study involved people with PBC whose alkaline phosphatase (ALP) level was between 1 and 1.67 times the upper limit of normal. The company describes ALP as a biochemical measure of disease activity.

At week 52, normalization of this marker was achieved by 85.3% of patients treated with Iqirvo. In the placebo arm, this proportion was 23.3%.

A publication in Hepatology and a therapeutic goal highlighted

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The results will be presented among the late-breaking data at The Liver Meeting 2026. They will be published simultaneously in Hepatology, the flagship journal of the AASLD.

For Ipsen, these results “add to a growing body of evidence supporting ALP normalization as an achievable therapeutic goal in PBC”.



Sector Pharmacie et biotechnologies › Pharmacie, vaccins et santé animale


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Context

Period
  • Period: T3 2026
Key reported figures
  • Revenue: 1 174 millions d'euros
  • Quarterly revenue: 1 174 millions d'euros
  • Revenue growth: 28,3 %

The information presented in this article is provided for informational purposes only and does not constitute an investment recommendation, an incentive to buy or sell a financial asset, or investment advice. Readers are invited to conduct their own research before making any decision.

Investments in the stock market involve risks, including the risk of capital loss. Past performance of an asset or market is no guarantee of future results. Any investment decision should be made taking into account your personal financial situation, objectives and risk tolerance.

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