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Last updated : 15/05/2026 - 17h35
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Valneva: Revenue Down 37% with a Net Loss of €32.1 Million in Q1 2026

Valneva has released its Q1 2026 results, showing a 37% decrease in revenue and a net loss of €32.1 million, compared to a €9.2 million loss in Q1 2025. Concurrently, the company has announced a reorganization plan aimed at reducing operational expenses by 25 to 35% and decreasing its global workforce by 10 to 15%, while maintaining a strengthened cash position of €105.3 million excluding April financing.


Valneva: Revenue Down 37% with a Net Loss of €32.1 Million in Q1 2026

Decline in Revenue, Commercial Portfolio in Transition

Valneva recorded a revenue of €30.9 million in Q1 2026, down 37% from €49.2 million in Q1 2025. Product sales amounted to €30.5 million compared to €48.6 million a year earlier. This decline reflects three major factors: the planned discontinuation of third-party product distribution (down 97.6%), a shift in delivery schedules to the U.S. Department of Defense (DoD) for the Ixiaro vaccine, and a change of distributor in Germany for Dukoral in January 2026. Within the travel vaccine portfolio, Ixiaro/Jespect generated €20.2 million (compared to €27.5 million the previous year), Dukoral €8.6 million (compared to €12.3 million), and Ixchiq €1.6 million (compared to €3.0 million), the latter decrease reflecting the absence of sporadic sales related to chikungunya outbreaks recorded in Q1 2025.

Compressed Margins and Worsened Operational Loss

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The net loss for the quarter reached €32.1 million, compared to €9.2 million in Q1 2025, marking a deterioration of 249%. This decline primarily stems from lower sales and exceptional effects at the cost of sales level (contract terminations, standard cost adjustments, inventory impairments). The gross margin on product sales (excluding Ixchiq) stood at 45.2% compared to 62.7% in Q1 2025. For Ixiaro alone, the margin fell to 50.8% from 72.6% in Q1 2025, hampered by higher production costs related to the transfer of production to the new Almeida facility in Scotland. The operational loss worsened to €23.7 million (Q1 2025: €6.0 million), while adjusted EBITDA came in at minus €18.2 million compared to minus €0.6 million in Q1 2025. However, non-direct production operational expenses decreased: commercial expenses at €7.0 million (vs. €10.4 million), general and administrative expenses at €8.2 million (vs. €9.0 million).

Reduction of Expenses and Consolidation of Cash Reserves

To secure its business model, Valneva launched a reorganization plan in April 2026 targeting a 10 to 15% reduction in its global workforce and a 25 to 35% decrease in operational expenses in 2026 compared to 2025. The company is focusing its resources on key strategic projects, including the Lyme disease vaccine in partnership with Pfizer. On the cash front, Valneva showed a remarkable improvement in its operational cash consumption: €0.3 million in Q1 2026 compared to €8.1 million in Q1 2025. The group's cash reserves stood at €105.3 million as of March 31, 2026 (versus €109.7 million on December 31, 2025), with an additional €37.0 million from a fundraising event in April 2026. For 2026, Valneva has revised its product sales outlook downwards, now expected to be between €135 and €150 million (versus €145 to €160 million previously), reflecting an unfavorable trend in the adoption of travel vaccines due to geopolitical factors. Total revenue is revised between €145 and €160 million, with other revenues confirmed. The company anticipates a normalization of gross margins once the exceptional effects of Q1 2026 are absorbed.



Sector Santé · Pharmacie Industrie Pharmaceutique


Assurance vie

Context

Period
  • Period: 9M 2025
Guidance from the release
  • Au troisième trimestre, nous avons continué à nous concentrer sur le renforcement de notre trésorerie, ce qui nous a permis de refinancer notre dette à des conditions financières plus avantageuses.
  • Chiffre d’affaires de 127,0 millions d’euros sur neuf mois (+8,9 %), ventes de 119,4 millions d’euros, trésorerie de 143,5 millions d’euros au 30/09/2025, perte nette 65,2 millions d’euros, EBITDA ajusté (37,7) millions d’euros. Guidance 2025 confirmée : chiffre d’affaires attendu entre 165 et 180 millions d’euros; ventes attendues entre 155 et 170 millions d'euros. Renforcement de la position financière via refinancement et ATMs; Phase 3 VALOR pour le vaccin Lyme en cours selon calendrier.
Risks mentioned
  • Suspension de la licence IXCHIQ ® aux États-Unis par la FDA (impact sur ventes segment voyageurs)
  • Risque de résultats cliniques défavorables pour les candidats (phase 3 VALOR pour Lyme, essais S4V2, VLA1601 incertitudes réglementaires)
  • Exposition aux fluctuations de change (impact négatif mentionné de 1,3 millions d’euros sur ventes, effets de change volontaires)
  • Dépendance à des partenaires de distribution et diminution des produits de tiers (arrêt de distribution de Rabipur/RabAvert et Encepur)
Opportunities identified
  • Résultats positifs potentiels de la Phase 3 VALOR (VLA15) pouvant mener à des demandes d'autorisation en 2026
  • Accord commercial avec CSL Seqirus en Allemagne pour stimuler la commercialisation des vaccins
  • Croissance des ventes d'IXCHIQ ® sur les marchés hors États-Unis et dans les PRFI (livraisons de substance active)
  • Potentiel du candidat S4V2 contre la shigellose (marché estimé > 500 millions de dollars/an)
  • Données positives de Phase 1 pour VLA1601 (Zika) et forte persistance d'anticorps pour IXCHIQ ® (95 % à 4 ans) comme avantage concurrentiel

The information presented in this article is provided for informational purposes only and does not constitute an investment recommendation, an incentive to buy or sell a financial asset, or investment advice. Readers are invited to conduct their own research before making any decision.

Investments in the stock market involve risks, including the risk of capital loss. Past performance of an asset or market is no guarantee of future results. Any investment decision should be made taking into account your personal financial situation, objectives and risk tolerance.

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