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Valneva Shares Drop 3.7% Amid Profit-Taking

Valneva's stock closed down 3.7% at 4.2680 euros on Thursday, January 15, in a technical correction context, with an RSI at 83 indicating an overbought zone after several bullish sessions. However, the momentum remains driven by the anticipation of Phase 3 results of the Lyme disease vaccine in the first half of 2026.


Valneva Shares Drop 3.7% Amid Profit-Taking

Technical Retracement Following Recent Gains

Valneva's shares fell 3.7% this Thursday to close at 4.2680 euros, after finishing the previous day at 4.43 euros. This correction occurs in a context of profit-taking, following several sessions of gains driven by investor optimism ahead of the J.P. Morgan Healthcare Conference in San Francisco held from January 12 to 14. Trading volumes remained moderate with 0.46% of the capital traded during the session, indicating a classic technical pause after a sustained upward movement. From a technical standpoint, the RSI stands at 83, well above the overbought threshold of 70, signaling an overheated situation that justifies a temporary pullback in the price. This pullback brings the stock back to its 50-day moving average at 3.85 euros, confirming that the underlying trend remains bullish. The price also remains above its 200-day moving average at 3.52 euros, validating a positive long-term dynamic. The resistance threshold at 4.43 euros, equivalent to the previous day's price, now becomes a key level to reconquer to restart the upward movement, while the support at 3.49 euros remains still distant.

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Today's correction is part of an overall favorable environment for biotechnology, with renewed investor interest in the VLA15 vaccine against Lyme disease developed in partnership with Pfizer. On January 6, Stifel bank reiterated its buy recommendation by raising its price target from 9.50 euros to 10 euros, representing a potential upside of 134% from the current price. The analyst is particularly optimistic about the upcoming publication of pivotal Phase 3 results expected in the first half of 2026, estimating that an efficacy between 70% and 80% would be favorably perceived by the market. VLA15 is currently the only vaccine candidate against Lyme disease in advanced clinical development, a pathology transmitted by ticks affecting about 476,000 people annually in the United States and 130,000 in Europe. Stifel estimates that the vaccine's maximum annual sales could reach 1.9 billion euros, given the increasing prevalence of the disease. Meanwhile, Valneva announced on December 31, 2025, the end of its licensing agreement with the Serum Institute of India concerning IXCHIQ, its vaccine against chikungunya, in order to take direct control of the marketing in endemic countries. In the first nine months of 2025, the laboratory reported revenue of 127 million euros, up 8.9% compared to the same period the previous year.



Sector Santé · Pharmacie Industrie Pharmaceutique


Assurance vie

Context

Period
  • Period: 9M 2025
Guidance from the release
  • Au troisième trimestre, nous avons continué à nous concentrer sur le renforcement de notre trésorerie, ce qui nous a permis de refinancer notre dette à des conditions financières plus avantageuses.
  • Chiffre d’affaires de 127,0 millions d’euros sur neuf mois (+8,9 %), ventes de 119,4 millions d’euros, trésorerie de 143,5 millions d’euros au 30/09/2025, perte nette 65,2 millions d’euros, EBITDA ajusté (37,7) millions d’euros. Guidance 2025 confirmée : chiffre d’affaires attendu entre 165 et 180 millions d’euros; ventes attendues entre 155 et 170 millions d'euros. Renforcement de la position financière via refinancement et ATMs; Phase 3 VALOR pour le vaccin Lyme en cours selon calendrier.
Risks mentioned
  • Suspension de la licence IXCHIQ ® aux États-Unis par la FDA (impact sur ventes segment voyageurs)
  • Risque de résultats cliniques défavorables pour les candidats (phase 3 VALOR pour Lyme, essais S4V2, VLA1601 incertitudes réglementaires)
  • Exposition aux fluctuations de change (impact négatif mentionné de 1,3 millions d’euros sur ventes, effets de change volontaires)
  • Dépendance à des partenaires de distribution et diminution des produits de tiers (arrêt de distribution de Rabipur/RabAvert et Encepur)
Opportunities identified
  • Résultats positifs potentiels de la Phase 3 VALOR (VLA15) pouvant mener à des demandes d'autorisation en 2026
  • Accord commercial avec CSL Seqirus en Allemagne pour stimuler la commercialisation des vaccins
  • Croissance des ventes d'IXCHIQ ® sur les marchés hors États-Unis et dans les PRFI (livraisons de substance active)
  • Potentiel du candidat S4V2 contre la shigellose (marché estimé > 500 millions de dollars/an)
  • Données positives de Phase 1 pour VLA1601 (Zika) et forte persistance d'anticorps pour IXCHIQ ® (95 % à 4 ans) comme avantage concurrentiel

The information presented in this article is provided for informational purposes only and does not constitute an investment recommendation, an incentive to buy or sell a financial asset, or investment advice. Readers are invited to conduct their own research before making any decision.

Investments in the stock market involve risks, including the risk of capital loss. Past performance of an asset or market is no guarantee of future results. Any investment decision should be made taking into account your personal financial situation, objectives and risk tolerance.

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