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Medincell: Uzedy Royalties Jump 42%, Net Loss Reaches €31.3M

Medincell continues its pivot towards recurring revenue: royalties from its first commercialized product, Uzedy (risperidone), have surged by 42% to €9.3M. However, the French biotech sees its net loss widen by 70%, from €18.4M to €31.3M, reflecting an acceleration in R&D investments and a lack of non-recurring revenues. The group highlights a strengthened cash position following the March 2026 fundraising, aimed at supporting the expansion of its pipeline and technology platform.


Medincell: Uzedy Royalties Jump 42%, Net Loss Reaches €31.3M

Uzedy Accelerates, but Lack of Milestones Weighs on Total Revenue

Revenue and other income amounted to €24.3M, down 12% compared to the previous year (€27.7M). This contraction masks two opposing dynamics. On one hand, Uzedy royalties have significantly increased: €9.3M compared to €6.5M the previous year, driven by a 54% increase in net sales by partner Teva, which amounted to $215M in US dollars. On the other hand, the absence of non-recurring revenues explains the overall decline. The 2024-25 fiscal year had benefited from €4.8M in milestone revenues related to the completion of the phase 3 study for Olanzapine. The 2025-26 fiscal year records none, while other partnership revenues fell to €10.2M (from €13.5M), reflecting the schedule of AbbVie's activities and global health programs.

Operating Expenses Accelerate, Deepening Operational Deficit

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Operating expenses reached €45.0M, up 17% or €6.5M in absolute terms. This increase is intentional: it responds to a declared strategy of expanding the pipeline and strengthening the technology platform. Research and development expenses rose to €26.5M (60% of total expenses), while commercial and marketing expenses increased to €4.2M, reflecting geographic expansion and the scaling up of teams. As a result, the current operating deficit widened to €20.7M, compared to a deficit of €10.8M the previous year. The net loss worsened further: €31.3M compared to €18.4M, an increase of 70%. This deterioration also stems from a financial loss of €10.6M, amplified by a non-monetary adjustment of €5.4M related to the revaluation of derivatives (EIB warrants) due to the rise in the share price.

Strengthened Cash Reserves but Profitability Still Distant

Medincell raised €48.2M in March 2026, attracting top American and European investors (Perceptive Advisors, Kurma, Affinity, Polar Capital). This operation brought the liquidity position to €84.8M (comprising €62.8M in cash and €22.0M in low-risk financial investments). Concurrently, operational cash flows are negative: €24.6M outflows, compared to €19.5M inflows the previous year, illustrating cash consumption related to expansion expenses. In the short term, the company is relying on two avenues to accelerate towards profitability: Teva's Olanzapine LAI, expected in Q4 2026 in the United States following FDA approval in February 2026, and the first AbbVie program, entering clinical study phase in 2027. In the short term, the company highlights the funds raised in March 2026 to support the expansion of the pipeline, partnership opportunities, and its LAI platform. The model of recurring royalties is emerging, but the leap to balance remains contingent on the commercial success of these key partners.



Sector Santé · Biotechnologies · Vaccins et laboratoires de recherche Biotechnologie


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Context

Period
  • Period: 9M 2025
Guidance from the release
  • We are pleased with the company’s growth and momentum.
  • Total income €14,1 million; Revenues €11,6 million (+35 %); UZEDY® royalties €4,2 million; Operating result €(6,6) million (improved 13 % year-over-year); Net result €(16 078) thousand; Cash and low-risk financial investments €53,5 million (incl. €49,8 million cash and €3,7 million low-risk investments); Net financial debt €17 629 thousand; NDA for Olanzapine LAI submitted to FDA on December 9, 2025; AbbVie partnership advancing with regulatory package expected in 2026.
Risks mentioned
  • Foreign exchange risk: weakness of USD vs EUR impacted revenues and generated ~€1 million FX losses
  • Dependency on partner commercialization (Teva) for UZEDY® royalties and sales forecasts
  • Regulatory risk: approvals (e.g., Olanzapine LAI) and acceptance for review uncertain
  • Financial volatility linked to fair value revaluation of EIB BSA warrants (non-cash €6,8 million impact)
Opportunities identified
  • Olanzapine LAI: NDA submitted and potential launch could be a major growth catalyst
  • UZEDY®: upward revision of 2025 net sales forecast by Teva (from $160 million to $190-200 million)
  • AbbVie partnership: first program advancing toward first-in-human trials (regulatory package expected 2026)
  • Gates Foundation financing: new $3 million envelope to advance mdc-STM malaria program
  • Expanded geographic approvals (Canada, South Korea) supporting broader commercialization

The information presented in this article is provided for informational purposes only and does not constitute an investment recommendation, an incentive to buy or sell a financial asset, or investment advice. Readers are invited to conduct their own research before making any decision.

Investments in the stock market involve risks, including the risk of capital loss. Past performance of an asset or market is no guarantee of future results. Any investment decision should be made taking into account your personal financial situation, objectives and risk tolerance.

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