Pfizer and Valneva: Their Lyme Disease Vaccine Effective Over 70%
Pfizer and Valneva announced on Monday the positive results of the phase 3 VALOR clinical trial of their Lyme disease vaccine candidate. The companies are preparing regulatory submissions following these results.
The vaccine candidate LB6V, formerly known as VLA15, demonstrated an efficacy rate of over 70% in preventing Lyme disease in individuals aged five years and older in the VALOR trial. The vaccine was well tolerated, and no safety concerns were identified at the time of data analysis.
Regulatory Submissions Planned
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Pfizer plans to submit the vaccine candidate to regulatory authorities. These results bolster confidence in the vaccine candidate's profile, according to the press release.
SectorPharmacie et biotechnologies›Vaccins et laboratoires de recherche
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Context
Period
Period: S1 2026
Key reported figures
Revenue: 65,8 millions d'euros
Quarterly revenue: 65,8 millions d'euros
Revenue growth: -32,6 %
EBITDA: -39,8 millions d'euros
Net income: -63,3 millions d'euros
Guidance from the release
Malgré l'impact négatif persistant du contexte géopolitique sur les voyages, Valneva a confirmé ses perspectives pour 2026
Risks mentioned
Impact négatif persistant du contexte géopolitique sur les voyages affectant les ventes de produits
Dépendance commerciale élevée envers les livraisons d'IXIARO au Département américain de la Défense avec calendrier incertain
Recentrage stratégique d'IXCHIQ sur les marchés endémiques affectant les perspectives commerciales du vaccin contre le chikungunya
Opportunities identified
Décisions réglementaires attendues pour le candidat vaccin LB6V contre la maladie de Lyme dans les 12 prochains mois
Amélioration attendue des marges brutes au second semestre après impact d'éléments non récurrents au S1 2026
Bénéfices futurs de l'initiative de restructuration visant à réduire la consommation de trésorerie et optimiser les opérations
Outlook / guidance
Expected revenue: 147,5 millions d'euros
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